Nov 20 21:40:08 ubuntu postfix/qmgr[12418]: 1EA5A2040813: from=app@mydom.com
Nov 20 21:40:08 ubuntu postfix/local[8895]: 1EA5A2040813: to=app@mydom.com, relay=local, delay=0.14, delays=0.09/0/0/0.06, dsn=5.1.1, status=bounced (unknown user: "app")
The fix is really simple. Remove or comment the following line in main.cf:
mydestination = $myhostname, $mydomain
Restart Postfix and you're ready to rock :)